Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559037 | 0.89 | MAPT (0.46) | PIK3CGPIK3CDALDH1A1GGT1MAPT | |
| SCHEMBL8555293 | 0.89 | PIK3CG (0.43) | PIK3CGPIK3CDALDH1A1GGT1MAPT | |
| SCHEMBL8553427 | 0.88 | PIK3CD (0.48) | PIK3CGPIK3CDALDH1A1GGT1MAPT | |
| SCHEMBL8561427 | 0.87 | ALDH1A1 (0.42) | ALDH1A1GRM2MAPTLMNASLC40A1 | |
| SCHEMBL8559918 | 0.87 | MAPT (0.41) | PIK3CGPIK3CDALDH1A1PIK3CAPIK3CB | |
| SCHEMBL8556318 | 0.85 | ALDH1A1 (0.44) | PIK3CDALDH1A1GGT1GRM2MAPT | |
| SCHEMBL8554227 | 0.85 | CCNT1 (0.49) | PIK3CGPIK3CDALDH1A1PIK3CAPIK3CB | |
| SCHEMBL8556636 | 0.85 | MAPT (0.44) | ALDH1A1MAPTLMNASLC40A1KDM4E | |
| SCHEMBL8556972 | 0.84 | ALDH1A1 (0.49) | PIK3CGALDH1A1GGT1MAPTLMNA | |
| SCHEMBL8559481 | 0.83 | ALDH1A1 (0.40) | PIK3CGPIK3CDALDH1A1GGT1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |