Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559037 | 0.89 | MAPT (0.46) | PIK3CGALDH1A1GGT1MAPTPIK3CD | |
| SCHEMBL8556822 | 0.89 | PIK3CG (0.43) | PIK3CGALDH1A1GGT1MAPTPIK3CD | |
| SCHEMBL8553427 | 0.88 | PIK3CD (0.48) | PIK3CGALDH1A1GGT1MAPTPIK3CD | |
| SCHEMBL8556712 | 0.87 | MAPT (0.42) | ALDH1A1MAPTPOLBLMNAPGR | |
| SCHEMBL8561447 | 0.87 | FBP1 (0.45) | ALDH1A1MAPTPOLBLMNAPGR | |
| SCHEMBL8554218 | 0.85 | ALDH1A1 (0.44) | ALDH1A1GGT1MAPTAVPR2GPR27 | |
| SCHEMBL8556141 | 0.85 | KAT6A (0.46) | ALDH1A1MAPTPOLBAVPR2GPR27 | |
| SCHEMBL8559341 | 0.85 | MAPT (0.44) | ALDH1A1MAPTLMNAPGRSLC40A1 | |
| SCHEMBL8556972 | 0.84 | ALDH1A1 (0.49) | PIK3CGALDH1A1GGT1MAPTPOLB | |
| SCHEMBL8553792 | 0.83 | MAPT (0.40) | ALDH1A1GGT1MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |