Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | IL1RN | P18510 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025139 | 0.91 | HDAC6 (0.42) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8560251 | 0.78 | HDAC6 (0.48) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8561382 | 0.78 | HSD11B1 (0.44) | HSD11B1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8555985 | 0.77 | NR4A2 (0.54) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8555624 | 0.76 | MAPT (0.58) | KDM4ERXFP1NPSR1MAPTMEN1 | |
| SCHEMBL8560630 | 0.76 | MAPT (0.49) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8557930 | 0.76 | HSD11B1 (0.44) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8557471 | 0.75 | MAPT (0.48) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8554937 | 0.74 | MAPT (0.44) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8555077 | 0.74 | PTGS2 (0.51) | HSD11B1KDM4ERXFP1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |