Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554059 | 0.87 | KDM1A (0.52) | PTGS2MAPTHSD11B1KDM4ERXFP1 | |
| SCHEMBL8555624 | 0.85 | MAPT (0.58) | MAPTKDM4ERXFP1PTPN2PTPN1 | |
| SCHEMBL8559708 | 0.81 | MAPT (0.46) | PTGS2MAPTKDM4ERXFP1PTPN2 | |
| SCHEMBL8560329 | 0.81 | PTGS2 (0.52) | PTGS2PTGS1MAPTHSD11B1KDM4E | |
| SCHEMBL8555123 | 0.76 | AR (0.51) | MAPTKDM4ERXFP1PTPN2PTPN1 | |
| SCHEMBL8473889 | 0.75 | EDNRB (0.54) | MAPTHSD11B1TSHR | |
| SCHEMBL8556824 | 0.74 | HSD11B1 (0.44) | MAPTHSD11B1KDM4ERXFP1PTPN2 | |
| SCHEMBL8560251 | 0.74 | HDAC6 (0.48) | MAPTHSD11B1KDM4ERXFP1PTPN2 | |
| SCHEMBL8560630 | 0.74 | MAPT (0.49) | MAPTHSD11B1KDM4ERXFP1PTPN2 | |
| SCHEMBL8560574 | 0.73 | MAPT (0.46) | MAPTHSD11B1KDM4EPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |