Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554882 | 0.87 | NR4A2 (0.57) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8560630 | 0.86 | MAPT (0.49) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8557471 | 0.85 | MAPT (0.48) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8556747 | 0.85 | RXRA (0.59) | KDM4EHPGDCYP2C19TSHRLMNA | |
| SCHEMBL8555234 | 0.84 | AURKA (0.44) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8554937 | 0.84 | MAPT (0.44) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8555950 | 0.83 | TSHR (0.44) | KDM4ENPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL8559306 | 0.83 | RXRA (0.60) | KDM4EALDH1A1HPGDCYP2C19TSHR | |
| SCHEMBL8558669 | 0.82 | TSHR (0.41) | HSD11B1KDM4ERXFP1NPSR1MAPT | |
| SCHEMBL8559925 | 0.82 | ALDH1A1 (0.45) | HSD11B1KDM4ERXFP1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |