Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 4/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555457 | 0.87 | DGAT2 (0.37) | DGAT2POLBHCRTR1CHEK2HTR2A | |
| SCHEMBL8552627 | 0.87 | POLB (0.37) | DGAT2POLBCHEK2HTR2ALTA4H | |
| SCHEMBL8555023 | 0.81 | KMT2A (0.35) | HCRTR1HCRTR2HTR2AKMT2APTGDR2 | |
| SCHEMBL8551701 | 0.80 | DGAT2 (0.39) | DGAT2POLBHCRTR1HCRTR2CHEK2 | |
| SCHEMBL8620953 | 0.78 | DGAT2 (0.41) | DGAT2CHEK2HTR2A | |
| SCHEMBL8553363 | 0.74 | NPY1R (0.48) | — | |
| SCHEMBL8551796 | 0.73 | DGAT2 (0.42) | DGAT2CHEK2 | |
| SCHEMBL8555474 | 0.70 | DGAT2 (0.36) | DGAT2 | |
| SCHEMBL8551675 | 0.68 | CHEK2 (0.44) | CHEK2PRMT5 | |
| SCHEMBL8555848 | 0.68 | DGAT2 (0.39) | DGAT2CHEK2PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |