Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.36 |
| ▸ | NPY1R | P25929 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555023 | 0.81 | KMT2A (0.35) | MAPTNPC1RAB9AHCRTR1HCRTR2 | |
| SCHEMBL8556902 | 0.80 | DGAT2 (0.37) | DGAT2POLBCHEK2HCRTR1HCRTR2 | |
| SCHEMBL8555457 | 0.76 | DGAT2 (0.37) | DGAT2POLBCHEK2HCRTR1PRMT5 | |
| SCHEMBL8552627 | 0.76 | POLB (0.37) | DGAT2POLBCHEK2NPY1RLTA4H | |
| SCHEMBL8550682 | 0.75 | DGAT2 (0.44) | DGAT2CHEK2NPY1R | |
| SCHEMBL8556963 | 0.73 | DGAT2 (0.41) | DGAT2NPC1RAB9ASMN1; SMN2NPY1R | |
| SCHEMBL8552606 | 0.73 | DGAT2 (0.43) | DGAT2CHEK2NPY1R | |
| SCHEMBL8552979 | 0.73 | NPC1 (0.41) | NPC1RAB9A | |
| SCHEMBL8553272 | 0.73 | MGLL (0.35) | DGAT2CHEK2HCRTR1HCRTR2PRMT5 | |
| SCHEMBL8556079 | 0.72 | RAB9A (0.55) | MAPTNPC1RAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |