Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 10/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.56 |
| ▸ | OXTR | P30559 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557265 | 0.94 | AVPR2 (0.58) | AVPR2AVPR1AOXTR | |
| SCHEMBL8559867 | 0.91 | RAB9A (0.47) | AVPR2AVPR1AGRM4 | |
| SCHEMBL8557947 | 0.91 | AVPR2 (0.53) | AVPR2AVPR1AOXTR | |
| SCHEMBL8558373 | 0.90 | AVPR2 (0.59) | AVPR2AVPR1AOXTR | |
| SCHEMBL8556908 | 0.89 | RAB9A (0.47) | AVPR2AVPR1A | |
| SCHEMBL8561432 | 0.89 | AVPR2 (0.55) | AVPR2AVPR1A | |
| SCHEMBL8561799 | 0.88 | AVPR2 (0.59) | AVPR2AVPR1AOXTR | |
| SCHEMBL8563330 | 0.88 | NPC1 (0.47) | AVPR2AVPR1A | |
| SCHEMBL8561944 | 0.87 | AVPR2 (0.48) | AVPR2AVPR1A | |
| SCHEMBL8561421 | 0.87 | AVPR2 (0.56) | AVPR2AVPR1AOXTRGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |