Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 10/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556908 | 0.93 | RAB9A (0.47) | RAB9AAVPR2AVPR1A | |
| SCHEMBL8561432 | 0.93 | AVPR2 (0.55) | RAB9AAVPR2AVPR1A | |
| SCHEMBL8561421 | 0.91 | AVPR2 (0.56) | AVPR2AVPR1AGRM4 | |
| SCHEMBL8556938 | 0.91 | AVPR2 (0.56) | AVPR2AVPR1AGRM4 | |
| SCHEMBL8564681 | 0.91 | AVPR2 (0.42) | AVPR2AVPR1A | |
| SCHEMBL8557265 | 0.89 | AVPR2 (0.58) | RAB9AAVPR2AVPR1A | |
| SCHEMBL8563330 | 0.89 | NPC1 (0.47) | RAB9AAVPR2AVPR1A | |
| SCHEMBL8560617 | 0.88 | AVPR1A (0.49) | RAB9AAVPR2AVPR1AGRM4 | |
| SCHEMBL8561799 | 0.87 | AVPR2 (0.59) | RAB9AAVPR2AVPR1A | |
| SCHEMBL8557787 | 0.86 | PNLIP (0.50) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |