Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559867 | 0.89 | RAB9A (0.47) | RAB9AAVPR2AVPR1A | |
| SCHEMBL8556938 | 0.88 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL8556908 | 0.86 | RAB9A (0.47) | NPC1RAB9AAVPR2AVPR1AKMT2A | |
| SCHEMBL8560629 | 0.86 | SMN1; SMN2 (0.51) | NPC1SMN1; SMN2RAB9AAVPR2AVPR1A | |
| SCHEMBL8561432 | 0.86 | AVPR2 (0.55) | NPC1RAB9AAVPR2AVPR1AKMT2A | |
| SCHEMBL8557265 | 0.86 | AVPR2 (0.58) | NPC1SMN1; SMN2RAB9AAVPR2AVPR1A | |
| SCHEMBL8561421 | 0.84 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL8561799 | 0.84 | AVPR2 (0.59) | NPC1SMN1; SMN2RAB9AAVPR2AVPR1A | |
| SCHEMBL8564681 | 0.84 | AVPR2 (0.42) | AVPR2AVPR1A | |
| SCHEMBL8558373 | 0.82 | AVPR2 (0.59) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |