Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559867 | 0.93 | RAB9A (0.47) | AVPR2AVPR1ARAB9A | |
| SCHEMBL8561944 | 0.93 | AVPR2 (0.48) | AVPR2AVPR1AMEN1KMT2ARAB9A | |
| SCHEMBL8563496 | 0.91 | AVPR2 (0.56) | AVPR2AVPR1AMEN1KMT2ARAB9A | |
| SCHEMBL8561421 | 0.90 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL8556938 | 0.89 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL8556908 | 0.89 | RAB9A (0.47) | AVPR2AVPR1AMEN1KMT2ARAB9A | |
| SCHEMBL8564681 | 0.88 | AVPR2 (0.42) | AVPR2AVPR1AJAK2JAK1TYK2 | |
| SCHEMBL8563330 | 0.86 | NPC1 (0.47) | AVPR2AVPR1AMEN1KMT2ARAB9A | |
| SCHEMBL8557265 | 0.86 | AVPR2 (0.58) | AVPR2AVPR1ARAB9ANPC1MAPT | |
| SCHEMBL8557927 | 0.85 | AVPR2 (0.51) | AVPR2AVPR1AGPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |