Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | OGA | O60502 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553993 | 0.93 | KDR (0.54) | ALDH1A1KDM4EATMTHRBOGA | |
| SCHEMBL8554363 | 0.91 | KDR (0.57) | KDM4EATMOGAKMT2AKDR | |
| SCHEMBL8555039 | 0.90 | ATM (0.62) | ACHEBACE1ALDH1A1KDM4EATM | |
| SCHEMBL8557154 | 0.87 | KDR (0.60) | ALDH1A1KDM4EOGAKMT2AMAPT | |
| SCHEMBL8557576 | 0.83 | MEN1 (0.52) | REV1ALDH1A1OGAKMT2ATSHR | |
| SCHEMBL8552887 | 0.82 | NR4A2 (0.47) | ALDH1A1KDM4EKMT2AKDRTSHR | |
| SCHEMBL8554568 | 0.82 | KDR (0.58) | ALDH1A1KDM4EATMKMT2AMAPT | |
| SCHEMBL18409631 | 0.81 | KCNH2 (0.49) | ACHEALDH1A1KDM4EATMKMT2A | |
| SCHEMBL8557836 | 0.79 | SLC29A1 (0.43) | ALDH1A1OGAKMT2AMAPTKDR | |
| SCHEMBL8553599 | 0.79 | KDR (0.48) | ACHEALDH1A1KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |
| US-5382584-A | Antiischemic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-17 | — | — | US | claimed |
| EP-0582164-A1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | Bristol-Myers Squibb Company (US) | 1994-02-09 | — | — | EP | claimed |