Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.57 |
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | RXRB | P28702 | 2/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | OGA | O60502 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553993 | 0.94 | KDR (0.54) | KDRRXRARXRBMEN1KMT2A | |
| SCHEMBL8555039 | 0.91 | ATM (0.62) | KDRRXRARXRBKCNA5MEN1 | |
| SCHEMBL8556969 | 0.91 | REV1 (0.53) | KDRMEN1KMT2AATMOGA | |
| SCHEMBL8557154 | 0.90 | KDR (0.60) | KDRKCNA5MEN1KMT2ALMNA | |
| SCHEMBL8552887 | 0.87 | NR4A2 (0.47) | KDRRXRARXRBMEN1KMT2A | |
| SCHEMBL8554568 | 0.83 | KDR (0.58) | KDRRXRARXRBMEN1KMT2A | |
| SCHEMBL18409505 | 0.81 | LMNA (0.56) | RXRARXRBLMNANR4A2KDM4E | |
| SCHEMBL8553599 | 0.80 | KDR (0.48) | KDRRXRARXRBMEN1KMT2A | |
| SCHEMBL18409351 | 0.79 | ALDH1A1 (0.54) | KDRRXRARXRBLMNANR4A2 | |
| SCHEMBL8557576 | 0.79 | MEN1 (0.52) | RXRARXRBMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |
| US-5382584-A | Antiischemic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-17 | — | — | US | claimed |
| EP-0582164-A1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | Bristol-Myers Squibb Company (US) | 1994-02-09 | — | — | EP | claimed |