Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | OGA | O60502 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | C5 | P01031 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554363 | 0.94 | KDR (0.57) | KDRLMNAOGANR4A2ATM | |
| SCHEMBL8555039 | 0.93 | ATM (0.62) | KDRLMNASMN1; SMN2OGAALDH1A1 | |
| SCHEMBL8556969 | 0.93 | REV1 (0.53) | KDROGAALDH1A1ATMMEN1 | |
| SCHEMBL8557154 | 0.90 | KDR (0.60) | KDRLMNASMN1; SMN2OGAALDH1A1 | |
| SCHEMBL8552887 | 0.86 | NR4A2 (0.47) | KDRLMNAALDH1A1NR4A2NR4A1 | |
| SCHEMBL8554568 | 0.86 | KDR (0.58) | KDRLMNAALDH1A1NR4A2NR4A1 | |
| SCHEMBL8553599 | 0.83 | KDR (0.48) | KDRLMNAALDH1A1NR4A2NR4A1 | |
| SCHEMBL18409351 | 0.83 | ALDH1A1 (0.54) | KDRLMNAALDH1A1NR4A2NR4A1 | |
| SCHEMBL8554274 | 0.80 | KDR (0.45) | KDRLMNASMN1; SMN2ALDH1A1NR4A2 | |
| SCHEMBL18409496 | 0.78 | NR4A2 (0.53) | LMNASMN1; SMN2ALDH1A1NR4A2NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |
| US-5382584-A | Antiischemic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-17 | — | — | US | claimed |
| EP-0582164-A1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | Bristol-Myers Squibb Company (US) | 1994-02-09 | — | — | EP | claimed |