Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GRN | P28799 | 4/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557036 | 1.00 | MAPK1 (0.55) | MAPK1ALDH1A1LMNAGRNSORT1 | |
| SCHEMBL8654231 | 0.87 | NOS3 (0.52) | LMNAKMT2ACA1CA2 | |
| SCHEMBL8555850 | 0.87 | NOS3 (0.52) | LMNAKMT2ACA1CA2 | |
| SCHEMBL8554539 | 0.85 | SHMT1 (0.50) | ALDH1A1KDM4EP2RX7 | |
| SCHEMBL8554540 | 0.85 | SHMT1 (0.50) | ALDH1A1KDM4EP2RX7 | |
| SCHEMBL4422723 | 0.84 | ATM (0.52) | MAPK1ALDH1A1LMNAGRNSORT1 | |
| SCHEMBL4422726 | 0.84 | ATM (0.52) | MAPK1ALDH1A1LMNAGRNSORT1 | |
| SCHEMBL7000904 | 0.83 | ALDH1A1 (0.53) | MAPK1ALDH1A1KMT2A | |
| SCHEMBL7000909 | 0.83 | ALDH1A1 (0.53) | MAPK1ALDH1A1KMT2A | |
| SCHEMBL8558519 | 0.83 | SDCBP (0.53) | ALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1080719-C | Substituted 1H-3-aryl-pyrrolidine-2,4-diones derivative | BAYER GMBH (DE) | 2002-03-13 | — | — | CN | disclosed |
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0668267-B1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1998-04-08 | — | — | EP | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| CN-1110680-A | Substituted 1H-3-aryl-pyrrolidine-2,4-diones derivative | BYLL GMBH (DE) | 1995-10-25 | — | — | CN | disclosed |
| EP-0668267-A1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |