Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27376595 | 0.83 | CASP1 (0.56) | BRD4ALDH1A1TSHRMAPTSLC5A1 | |
| SCHEMBL9687541 | 0.82 | BRD4 (0.50) | BRD4ALDH1A1TSHRMAPTSLC5A2 | |
| SCHEMBL9687662 | 0.82 | BRD4 (0.53) | BRD4ALDH1A1TSHRMAPTALOX15 | |
| SCHEMBL9686537 | 0.82 | BRD4 (0.53) | BRD4ALDH1A1TSHRMAPTALOX15 | |
| SCHEMBL8624433 | 0.80 | SLC5A1 (0.51) | BRD4ALDH1A1TSHRMAPTSLC5A1 | |
| SCHEMBL27376459 | 0.80 | BRD4 (0.48) | BRD4ALDH1A1CFTRKDM4EMEN1 | |
| SCHEMBL30806562 | 0.80 | BRD4 (0.48) | BRD4ALDH1A1CFTRKDM4EMEN1 | |
| SCHEMBL8557086 | 0.79 | TSHR (0.67) | BRD4ALDH1A1TSHRMAPTSLC5A1 | |
| SCHEMBL8130592 | 0.78 | TERT (0.48) | ALDH1A1TSHRMAPTSLC5A1SLC5A2 | |
| SCHEMBL30806670 | 0.76 | PIK3CG (0.48) | BRD4ALDH1A1TSHRSLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5077401-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-4902335-A | Benzo-fused cyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0296416-A1 | Benzo-anellated cyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1988-12-28 | — | — | EP | disclosed |