Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555940 | 0.85 | ADORA3 (0.41) | MAPTKDM4EADORA3SMN1; SMN2GPBAR1 | |
| SCHEMBL8556878 | 0.82 | PPARD (0.50) | MAPTMEN1KDM4EL3MBTL1ADORA3 | |
| SCHEMBL8554714 | 0.78 | PARP10 (0.57) | KMT2AMAPTMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL8559076 | 0.78 | KMT2A (0.40) | KMT2AMAPTMEN1KDM4EGPBAR1 | |
| SCHEMBL8557020 | 0.78 | GPBAR1 (0.46) | KMT2AMAPTNPC1SMN1; SMN2GPBAR1 | |
| SCHEMBL8626716 | 0.77 | NPC1 (0.54) | KMT2AMAPTMEN1KDM4EL3MBTL1 | |
| SCHEMBL8554930 | 0.77 | GPBAR1 (0.62) | GPBAR1 | |
| SCHEMBL8559814 | 0.76 | PARP10 (0.45) | KMT2AMEN1ADORA3NPC1SMN1; SMN2 | |
| SCHEMBL8622650 | 0.76 | NPC1 (0.53) | KMT2AMAPTMEN1KDM4EL3MBTL1 | |
| SCHEMBL8555090 | 0.76 | GPBAR1 (0.61) | GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |