Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555940 | 0.89 | ADORA3 (0.41) | PARP10SMN1; SMN2MAPK14SMOPDE10A | |
| SCHEMBL8554714 | 0.88 | PARP10 (0.57) | PARP10SMN1; SMN2MAPK14SMOMEN1 | |
| SCHEMBL8557214 | 0.84 | ADORA3 (0.47) | NPC1SMN1; SMN2MEN1KMT2AADORA3 | |
| SCHEMBL8554930 | 0.80 | GPBAR1 (0.62) | FFAR1PDE10AGPBAR1 | |
| SCHEMBL8555090 | 0.79 | GPBAR1 (0.61) | FFAR1PDE10AGPBAR1 | |
| SCHEMBL8557020 | 0.79 | GPBAR1 (0.46) | NPC1SMN1; SMN2FFAR1KMT2APDE10A | |
| SCHEMBL8626716 | 0.76 | NPC1 (0.54) | NPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8557149 | 0.76 | KMT2A (0.38) | NPC1SMN1; SMN2MEN1KMT2AGPBAR1 | |
| SCHEMBL8622650 | 0.76 | NPC1 (0.53) | NPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8559076 | 0.75 | KMT2A (0.40) | PARP10MAPK14SMOMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |