Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 13/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | PKLR | P30613 | 1/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | BRD1 | O95696 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481312 | 0.87 | PKM (0.48) | DAGLACYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8557971 | 0.87 | ATM (0.56) | DAGLACYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8557090 | 0.80 | PKM (0.51) | DAGLACYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8553826 | 0.80 | DAGLA (0.51) | DAGLACYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8558063 | 0.78 | CYP3A4 (0.57) | DAGLACYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7825817 | 0.75 | HIF1A (0.49) | — | |
| SCHEMBL8558762 | 0.75 | DAGLA (0.56) | DAGLACYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8487793 | 0.75 | DAGLA (0.59) | DAGLACYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27482783 | 0.74 | DAGLA (0.52) | DAGLACYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7820690 | 0.74 | ATM (0.39) | ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1185153-A | Benzopyrans and pharmaceutical composition contg. same | CIBA GEIGY AG (CH) | 1998-06-17 | — | — | CN | disclosed |
| EP-0828733-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Novartis AG (CH) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037490-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-11-28 | — | — | WO | disclosed |