Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 9/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557971 | 0.85 | ATM (0.56) | DAGLACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8487793 | 0.82 | DAGLA (0.59) | DAGLACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7821527 | 0.77 | ESR1 (0.46) | HIF1AEPAS1ESR1TSHRMAPK1 | |
| SCHEMBL12355590 | 0.75 | DAGLA (0.87) | DAGLACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8557486 | 0.75 | DAGLA (0.49) | DAGLACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3380011 | 0.75 | DAGLA (0.55) | DAGLACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2242243 | 0.74 | DAGLA (0.53) | DAGLACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8553826 | 0.74 | DAGLA (0.51) | DAGLACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8557904 | 0.74 | PKM (0.73) | DAGLACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7812015 | 0.74 | HIF1A (0.69) | HIF1AEPAS1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1185153-A | Benzopyrans and pharmaceutical composition contg. same | CIBA GEIGY AG (CH) | 1998-06-17 | — | — | CN | disclosed |
| EP-0828733-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Novartis AG (CH) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037490-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-11-28 | — | — | WO | disclosed |