Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 11/20 | 0.51 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558063 | 0.88 | CYP3A4 (0.57) | DAGLAABHD6CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL8557971 | 0.86 | ATM (0.56) | DAGLAABHD6CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL27482783 | 0.82 | DAGLA (0.52) | DAGLAABHD6CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL8557486 | 0.80 | DAGLA (0.49) | DAGLAABHD6CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL8557090 | 0.79 | PKM (0.51) | DAGLAABHD6CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL27481312 | 0.79 | PKM (0.48) | DAGLAABHD6CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL21950002 | 0.76 | MAPT (0.55) | DAGLAABHD6KCNH2MAPTPLCG2 | |
| SCHEMBL7822894 | 0.76 | HIF1A (0.57) | PGRHIF1AEPAS1 | |
| SCHEMBL2245024 | 0.74 | DAGLA (0.84) | DAGLAABHD6CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL7821015 | 0.74 | PGR (0.44) | CYP3A4CYP2C19MAPTPGRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828733-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Novartis AG (CH) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037490-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-11-28 | — | — | WO | disclosed |