SCHEMBL8557501

SCHEMBL8557501

CC(C)c1ccc(S(=O)(=O)N=C=O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
MAPT P10636 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
THRB P10828 1/20 0.48
HTT P42858 1/20 0.48
MCL1 Q07820 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
LMNA P02545 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43
POLB P06746 2/20 0.42
NSD2 O96028 1/20 0.42
ATM Q13315 1/20 0.42
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
MCOLN3 Q8TDD5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5653955 0.83 F2 (0.37) ALDH1A1MAPTKMT2AHTTLMNA
SCHEMBL22302 0.78 F2 (0.52) ALDH1A1MEN1KMT2ASMN1; SMN2HTT
SCHEMBL1125078 0.78 F2 (0.52) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL11871006 0.78 HTR2A (0.43) ALDH1A1MAPTTHRBLMNAKDM4E
SCHEMBL28209363 0.74 F2 (0.48) ALDH1A1MEN1KMT2ASMN1; SMN2HTT
SCHEMBL11870998 0.74 LMNA (0.39) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL5655146 0.74 F2 (0.52) ALDH1A1MAPTTDP1CA12CA1
SCHEMBL1124662 0.74 F2 (0.52) ALDH1A1MEN1KMT2ACA1CA2
SCHEMBL8553087 0.73 ALDH1A1 (0.52) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL1945898 0.73 F2 (0.56) ALDH1A1MAPTMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133363-B2 Stabilized urethane based surface coating BLUM HOLGER (CH) 2015-09-15 US disclosed
US-20150011690-A1 STABILIZED URETHANE BASED SURFACE COATING BLUM HOLGER (CH) 2015-01-08 US disclosed
EP-2686358-B1 STABILIZED URETHANE BASED SURFACE COATING BLUM HOLGER (CH) 2014-11-19 EP disclosed
EP-2686358-A1 STABILIZED URETHANE BASED SURFACE COATING Blum, Holger (CH) 2014-01-22 EP disclosed
WO-2013139388-A1 STABILIZED URETHANE BASED SURFACE COATING BLUM HOLGER (CH) 2013-09-26 WO disclosed
EP-0885890-A1 SULFONYLUREIDOPYRAZOLE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1998-12-23 EP disclosed
EP-0565754-B1 Stabilized coating composition on the basis of urethaneprepolymers having free isocyanate groups BLUM HOLGER (DE) 1995-12-27 EP disclosed
US-5338786-A Storage stability; containing a thiophene compounds and an arylsulphoryisocyanate compound CHEMICAL INVESTMENTS, LTD. (GB) 1994-08-16 US disclosed
EP-0565754-A1 Stabilized coating composition on the basis of urethaneprepolymers having free isocyanate groups Blum, Holger (DE) 1993-10-20 EP disclosed