Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973844 | 0.84 | AHR (0.33) | AHR | |
| SCHEMBL854920 | 0.79 | AHR (0.53) | AHRCYP3A4 | |
| SCHEMBL2012796 | 0.78 | SLC22A12 (0.35) | ALDH1A1AHRHPGD | |
| SCHEMBL2622604 | 0.72 | ALDH1A1 (0.45) | ALDH1A1AHRCYP3A4HPGDCRHBP | |
| SCHEMBL854597 | 0.71 | PTGS1 (0.43) | — | |
| SCHEMBL2177901 | 0.71 | AHR (0.55) | ALDH1A1AHRCYP3A4HPGD | |
| SCHEMBL854913 | 0.70 | APP (0.33) | — | |
| SCHEMBL854874 | 0.70 | AHR (0.39) | AHR | |
| SCHEMBL9227835 | 0.70 | AHR (0.48) | ALDH1A1AHRHSD17B10 | |
| SCHEMBL3578088 | 0.69 | TSHR (0.49) | ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432762-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| EP-2349994-A1 | PESTICIDAL (HETERO) ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010133336-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010043315-A1 | PESTICIDAL (HETERO) ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-04-22 | — | — | WO | disclosed |
| WO-2008150393-A1 | 3-CYANO-4-TRIAZOLYL PHENYLISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-11 | — | — | WO | disclosed |