Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855775 | 0.78 | ALDH1A1 (0.36) | AHRALDH1A1HPGD | |
| SCHEMBL3973844 | 0.76 | AHR (0.33) | AHR | |
| SCHEMBL854920 | 0.71 | AHR (0.53) | AHR | |
| SCHEMBL19136489 | 0.70 | ALDH1A1 (0.46) | SLC22A12KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL4741271 | 0.70 | GABRB3 (0.47) | SLC22A12KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL5605187 | 0.70 | MEN1 (0.33) | MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL28249113 | 0.67 | FBP1 (0.47) | KDM4EMEN1ALDH1A1GAAKMT2A | |
| SCHEMBL21064821 | 0.66 | TRPV4 (0.41) | SLC22A12KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL24983940 | 0.65 | GABRA1 (0.36) | KDM4EMEN1ALDH1A1GLAGAA | |
| SCHEMBL952362 | 0.65 | ALDH1A1 (0.45) | AHRKDM4EMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507230-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | Syngenta Participations AG (CH) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011067272-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |