Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555742 | 0.88 | PLAT (0.36) | CTSKNR3C1KCNA3JAK3BTK | |
| SCHEMBL8555714 | 0.82 | NR3C1 (0.45) | NR3C1DRD2KCNA3P2RX7 | |
| SCHEMBL8553207 | 0.71 | P2RY12 (0.42) | NR3C1 | |
| SCHEMBL8557781 | 0.70 | — | — | |
| SCHEMBL8553968 | 0.70 | ALOX15 (0.48) | CTSKPOLBNR3C1JAK3BTK | |
| SCHEMBL31082113 | 0.70 | KMT2A (0.34) | CTSKBTK | |
| SCHEMBL31081835 | 0.70 | KMT2A (0.34) | CTSKBTK | |
| SCHEMBL18300633 | 0.66 | DGAT1 (0.41) | CTSK | |
| SCHEMBL31735465 | 0.64 | PDE7A (0.39) | POLBNR3C1PDE7A | |
| SCHEMBL21115006 | 0.64 | GPR119 (0.39) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |