Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 11/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.42 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556562 | 0.87 | KCNK3 (0.44) | PNLIPKCNK3KCNK9RXFP1AVPR2 | |
| SCHEMBL8559867 | 0.86 | RAB9A (0.47) | AVPR2AVPR1A | |
| SCHEMBL8561421 | 0.86 | AVPR2 (0.56) | AVPR2AVPR1AOXTR | |
| SCHEMBL8556938 | 0.84 | AVPR2 (0.56) | PNLIPAVPR2AVPR1AOXTR | |
| SCHEMBL8556908 | 0.84 | RAB9A (0.47) | AVPR2AVPR1A | |
| SCHEMBL8561432 | 0.84 | AVPR2 (0.55) | AVPR2AVPR1AGPR27 | |
| SCHEMBL8561799 | 0.82 | AVPR2 (0.59) | AVPR2AVPR1AOXTR | |
| SCHEMBL8558373 | 0.82 | AVPR2 (0.59) | AVPR2AVPR1AOXTR | |
| SCHEMBL8564681 | 0.82 | AVPR2 (0.42) | AVPR2AVPR1A | |
| SCHEMBL8557265 | 0.82 | AVPR2 (0.58) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |