Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025121 | 0.95 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNASCN9AMEN1 | |
| SCHEMBL8561122 | 0.92 | MAPT (0.44) | ALDH1A1MAPTLMNASCN9AMEN1 | |
| SCHEMBL8559957 | 0.91 | MAPT (0.47) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL9025116 | 0.89 | MAPT (0.42) | ALDH1A1MAPTLMNASCN9ASLC40A1 | |
| SCHEMBL8559393 | 0.88 | KMO (0.47) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL8558062 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL9026442 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL8561410 | 0.86 | PTGS2 (0.47) | ALDH1A1MAPTLMNAMAPK1SLC40A1 | |
| SCHEMBL8558989 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL8559259 | 0.85 | MAPT (0.47) | ALDH1A1MAPTLMNASLC40A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699192-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-06 | — | — | EP | claimed |
| WO-1994027980-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1994-12-08 | — | — | WO | claimed |
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |