Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.46 |
| ▸ | F2 | P00734 | 7/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558127 | 0.86 | F10 (0.47) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9031768 | 0.83 | KMT2A (0.57) | ALDH1A1PLAUHPNKMT2AST14 | |
| SCHEMBL20436792 | 0.83 | KMT2A (0.55) | F2ALDH1A1FBP1KMT2ANPC1 | |
| SCHEMBL9030021 | 0.78 | F2 (0.47) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9031248 | 0.78 | F2 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9029174 | 0.78 | ALDH1A1 (0.45) | F10F2ALDH1A1FBP1PLAU | |
| SCHEMBL8558495 | 0.77 | ABCC9 (0.46) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL9031533 | 0.73 | F2 (0.51) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8257058 | 0.72 | KMT2A (0.51) | ALDH1A1FBP1KMT2A | |
| SCHEMBL10583477 | 0.71 | ALDH1A1 (0.50) | ALDH1A1FBP1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |