Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557162 | 1.00 | ALDH1A1 (0.57) | ALDH1A1NPSR1TAS1R3TAS1R1MEN1 | |
| SCHEMBL8558206 | 0.89 | NOS3 (0.52) | ALDH1A1NPSR1TAS1R3TAS1R1MEN1 | |
| SCHEMBL8652110 | 0.89 | NOS3 (0.52) | ALDH1A1NPSR1TAS1R3TAS1R1MEN1 | |
| SCHEMBL8558522 | 0.87 | SDCBP (0.53) | ALDH1A1NPSR1THRBP2RX7 | |
| SCHEMBL8558519 | 0.87 | SDCBP (0.53) | ALDH1A1NPSR1THRBP2RX7 | |
| SCHEMBL8654991 | 0.87 | MEN1 (0.55) | ALDH1A1NPSR1MEN1KMT2ALMNA | |
| SCHEMBL8555896 | 0.87 | MEN1 (0.55) | ALDH1A1NPSR1MEN1KMT2ALMNA | |
| SCHEMBL20752921 | 0.86 | ALDH1A1 (0.50) | ALDH1A1NPSR1TAS1R3TAS1R1MEN1 | |
| SCHEMBL20752911 | 0.86 | ALDH1A1 (0.50) | ALDH1A1NPSR1TAS1R3TAS1R1MEN1 | |
| SCHEMBL20752917 | 0.86 | ALDH1A1 (0.50) | ALDH1A1NPSR1TAS1R3TAS1R1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |