Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559699 | 0.91 | MAPT (0.43) | ALDH1A1MAPTTSHRKDM4ELIMK2 | |
| SCHEMBL8560019 | 0.91 | MAPT (0.43) | ALDH1A1MAPTTSHRKDM4ELIMK2 | |
| SCHEMBL8559236 | 0.91 | KMT2A (0.47) | ALDH1A1MAPTTSHRKDM4ELIMK2 | |
| SCHEMBL8558562 | 0.91 | MAPT (0.43) | ALDH1A1MAPTTSHRKDM4ELIMK2 | |
| SCHEMBL9026498 | 0.89 | MAPT (0.43) | ALDH1A1MAPTTSHRKDM4ELIMK2 | |
| SCHEMBL8560574 | 0.88 | MAPT (0.46) | ALDH1A1MAPTTSHRKDM4ELIMK2 | |
| SCHEMBL8560132 | 0.87 | MEN1 (0.47) | ALDH1A1MAPTTSHRKDM4ELIMK2 | |
| SCHEMBL8557996 | 0.87 | MAPT (0.46) | ALDH1A1MAPTTSHRLIMK2SLC40A1 | |
| SCHEMBL8557471 | 0.86 | MAPT (0.48) | ALDH1A1MAPTTSHRKDM4ELIMK2 | |
| SCHEMBL8560000 | 0.85 | KMO (0.47) | ALDH1A1MAPTTSHRKDM4ELIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |