Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557471 | 0.92 | MAPT (0.48) | MAPTALDH1A1LIMK2MEN1KMT2A | |
| SCHEMBL8557996 | 0.90 | MAPT (0.46) | MAPTALDH1A1LIMK2LMNAGAA | |
| SCHEMBL8560337 | 0.88 | MAPT (0.50) | MAPTALDH1A1LIMK2MEN1KMT2A | |
| SCHEMBL8559708 | 0.88 | MAPT (0.46) | MAPTALDH1A1LIMK2MEN1KMT2A | |
| SCHEMBL8560132 | 0.88 | MEN1 (0.47) | MAPTALDH1A1LIMK2MEN1KMT2A | |
| SCHEMBL8558253 | 0.88 | ALDH1A1 (0.44) | MAPTALDH1A1LIMK2LMNAGAA | |
| SCHEMBL8556972 | 0.88 | ALDH1A1 (0.49) | MAPTALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL8559699 | 0.85 | MAPT (0.43) | MAPTALDH1A1LIMK2LMNAGAA | |
| SCHEMBL8558562 | 0.85 | MAPT (0.43) | MAPTALDH1A1LIMK2KMT2ALMNA | |
| SCHEMBL8559236 | 0.85 | KMT2A (0.47) | MAPTALDH1A1LIMK2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699192-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-06 | — | — | EP | claimed |
| WO-1994027980-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1994-12-08 | — | — | WO | claimed |
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |