Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155454 | 0.72 | LMNA (0.49) | PDPK1SCN3AFAAHPRSS1PRSS2 | |
| Ethylbenzene SCHEMBL27335499 | 0.72 | TP53 (0.42) | PDPK1SCN3AKDM4EPLA2G4ALMNA | |
| SCHEMBL9097096 | 0.70 | POLB (0.50) | PDPK1LMNAKMT2ASLC40A1ALDH1A1 | |
| SCHEMBL20679918 | 0.70 | NAMPT (0.46) | SCN3AKDM4ELMNAKMT2ASMN1; SMN2 | |
| SCHEMBL28038637 | 0.70 | TRPA1 (0.42) | PDPK1SCN3AFAAHPRSS1PRSS2 | |
| SCHEMBL9412348 | 0.69 | CA1 (0.52) | FAAHPRSS1PRSS2ELANEPRTN3 | |
| SCHEMBL20679889 | 0.69 | CYP2A6 (0.41) | LMNASMN1; SMN2SLC40A1ALDH1A1 | |
| Benzene SCHEMBL28463436 | 0.67 | ACP1 (0.41) | PDPK1LMNASMN1; SMN2SLC40A1ALDH1A1 | |
| SCHEMBL28370949 | 0.67 | KMT2A (0.42) | PDPK1CA1CA2CA9LMNA | |
| SCHEMBL502516 | 0.66 | ABCC9 (0.44) | PDPK1KDM4ELMNAKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |