Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558748 | 0.77 | METAP1 (0.39) | ACHE | |
| SCHEMBL7834401 | 0.77 | TBXAS1 (0.36) | — | |
| SCHEMBL8557548 | 0.75 | METAP1 (0.38) | — | |
| SCHEMBL8555982 | 0.75 | METAP1 (0.38) | — | |
| SCHEMBL8880656 | 0.73 | METAP1 (0.38) | — | |
| SCHEMBL8558771 | 0.72 | KDM4E (0.40) | ACHE | |
| SCHEMBL8880563 | 0.71 | GABRG2 (0.38) | — | |
| SCHEMBL8881385 | 0.71 | GABRG2 (0.41) | — | |
| SCHEMBL8881176 | 0.71 | CYP19A1 (0.43) | — | |
| SCHEMBL8090657 | 0.70 | GABRA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820455-A1 | 5H, 10H-IMIDAZO [1,2-a]INDENO [1,2-e]PYRAZIN-4-ONE DERIVATIVES, PREPARATION THEREOF, AND DRUGS CONTAINING SAID DERIVATIVES | Aventis Pharma S.A. (FR) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996031511-A1 | 5H,10H-IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZIN-4-ONE DERIVATIVES, PREPARATION THEREOF, AND DRUGS CONTAINING SAID DERIVATIVES | RHONE-POULENC RORER S.A. (FR) | 1996-10-10 | — | — | WO | disclosed |