Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HNF4A | P41235 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556306 | 0.81 | KDR (0.34) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| SCHEMBL8554052 | 0.80 | LMNA (0.37) | CYP3A4NPC1RAB9ALMNAPOLB | |
| SCHEMBL8552834 | 0.80 | NPC1 (0.31) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| SCHEMBL8595610 | 0.71 | CTSB (0.39) | TSHRALDH1A1SIGMAR1HPRT1LMNA | |
| SCHEMBL8554926 | 0.68 | HSP90AA1 (0.42) | TSHRNCEH1CYP3A4HSP90AA1CRHBP | |
| SCHEMBL8555244 | 0.67 | CTSB (0.39) | TSHRNCEH1ALDH1A1SIGMAR1RAB9A | |
| SCHEMBL12363753 | 0.64 | TSHR (0.64) | TSHRNCEH1CYP3A4HSP90AA1CRHBP | |
| SCHEMBL1710125 | 0.64 | TSHR (1.00) | TSHRNCEH1CYP3A4HSP90AA1CRHBP | |
| SCHEMBL3071816 | 0.64 | TSHR (0.62) | TSHRNCEH1CYP3A4HSP90AA1CRHBP | |
| SCHEMBL8554676 | 0.64 | RAB9A (0.40) | CYP3A4ALDH1A1RAB9AHPRT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | claimed |
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |