Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558985 | 0.80 | TSHR (0.45) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL8556306 | 0.77 | KDR (0.34) | NPC1MAPTRAB9ANPSR1KDM4E | |
| SCHEMBL8554052 | 0.77 | LMNA (0.37) | NPC1MAPTRAB9ALMNAPOLB | |
| SCHEMBL8552830 | 0.71 | RAB9A (0.37) | RAB9AHTTLMNAALDH1A1 | |
| SCHEMBL8554881 | 0.69 | ALDH1A1 (0.35) | MAPTRAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10688327 | 0.69 | S100A4 (0.36) | NPC1MAPTRAB9ANPSR1KDM4E | |
| SCHEMBL9770602 | 0.68 | CTSB (0.49) | MAPTKDM4EHTTLMNAPOLB | |
| SCHEMBL3342318 | 0.67 | TSHR (0.51) | NPC1MAPTRAB9ANPSR1KDM4E | |
| SCHEMBL8555441 | 0.66 | DYRK1A (0.39) | MAPTNPSR1KDM4EHTTPOLB | |
| SCHEMBL8552840 | 0.66 | MAPT (0.36) | NPC1MAPTRAB9ANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | claimed |
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |