Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558985 | 0.80 | TSHR (0.45) | LMNAPOLBKMT2ACYP3A4GAA | |
| SCHEMBL8555441 | 0.77 | DYRK1A (0.39) | POLBKMT2ACTSBARMEN1 | |
| SCHEMBL8556306 | 0.77 | KDR (0.34) | LMNAPOLBKMT2AS100A4MEN1 | |
| SCHEMBL8552834 | 0.77 | NPC1 (0.31) | LMNAPOLBNPC1RAB9AMAPT | |
| SCHEMBL8554050 | 0.70 | RAB9A (0.42) | LMNAPOLBKMT2ACYP3A4GAA | |
| SCHEMBL8595610 | 0.68 | CTSB (0.39) | LMNAKMT2ACTSBARMEN1 | |
| SCHEMBL2285808 | 0.67 | CYP3A4 (0.70) | LMNACYP3A4CTSBS100A4NPC1 | |
| SCHEMBL29674860 | 0.67 | CYP3A4 (0.70) | LMNACYP3A4CTSBS100A4NPC1 | |
| SCHEMBL19033408 | 0.62 | CYP3A4 (0.57) | LMNACYP3A4S100A4NPC1RAB9A | |
| SCHEMBL8554443 | 0.62 | CTSB (0.43) | LMNAPOLBKMT2AGAACTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | claimed |
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | claimed |
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |