SCHEMBL10106100

SCHEMBL10106100

CCCCCCCC[N+](CCCCCCCC)(CCCCCCCC)Cc1c2ccccc2cc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 4/20 0.42
MAPT P10636 1/20 0.42
SLC22A1 O15245 2/20 0.42
HTR2A P28223 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TP53 P04637 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
ALOX12 P18054 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HTT P42858 2/20 0.41
SLC22A2 O15244 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12704930 0.93 HTR2A (0.44) DNM1MAPTSLC22A1HTR2AL3MBTL1
SCHEMBL1039347 0.90 DNM1 (0.39) DNM1MAPTSLC22A1HTR2AL3MBTL1
SCHEMBL17323593 0.79 HTR2A (0.50) MAPTHTR2AL3MBTL1SMN1; SMN2MEN1
SCHEMBL5116260 0.78 MAPT (0.55) MAPTHTR2AL3MBTL1ALDH1A1HSD17B10
SCHEMBL16267095 0.78 MAPT (0.55) MAPTHTR2AL3MBTL1ALDH1A1HSD17B10
SCHEMBL8379349 0.78 MAPT (0.55) MAPTHTR2AL3MBTL1ALDH1A1HSD17B10
SCHEMBL16267023 0.78 MAPT (0.55) MAPTHTR2AL3MBTL1ALDH1A1HSD17B10
SCHEMBL16267503 0.78 MAPT (0.55) MAPTHTR2AL3MBTL1ALDH1A1HSD17B10
SCHEMBL299862 0.75 MAPT (0.53) MAPTHTR2AL3MBTL1ALDH1A1HSD17B10
SCHEMBL8559161 0.75 DNM1 (0.44) DNM1SLC22A1TP53SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8853290-B2 Photosensitive composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2014-10-07 US disclosed
US-8329771-B2 Photobase generator SAN-APRO LIMITED (JP) 2012-12-11 US disclosed
US-20120142806-A1 PHOTOSENSITIVE COMPOSITION SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2012-06-07 US disclosed
US-20110028585-A1 PHOTOBASE GENERATOR SAN-APRO LIMITED (JP) 2011-02-03 US disclosed
US-20110028585-A1 PHOTOBASE GENERATOR SAN-APRO LIMITED (JP) 2011-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028585-A1 PHOTOBASE GENERATOR CCKBR, XDH, PPOX DNM1 1663/4885MAPT 1753/4885SLC22A1 4070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.