Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.38 |
| ▸ | RXRB | P28702 | 5/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555759 | 0.93 | PTGS2 (0.39) | RXRAPTGS2PTGS1NR4A2RXRB | |
| SCHEMBL8561125 | 0.93 | PTGS2 (0.47) | RXRAPTGS2PTGS1NR4A2RXRB | |
| SCHEMBL8559961 | 0.92 | RXRA (0.43) | RXRAPTGS2PTGS1SCN9AMAPT | |
| SCHEMBL8559396 | 0.88 | RXRA (0.48) | RXRAPTGS2PTGS1NR4A2RXRB | |
| SCHEMBL8558066 | 0.88 | NR4A2 (0.40) | RXRAPTGS2PTGS1NR4A2RXRB | |
| SCHEMBL8561414 | 0.87 | PTGS2 (0.47) | RXRAPTGS2PTGS1SCN9AMAPT | |
| SCHEMBL7508972 | 0.87 | PTGS2 (0.46) | RXRAPTGS2PTGS1RXRBRXRG | |
| SCHEMBL8558990 | 0.87 | NR4A2 (0.39) | RXRAPTGS2PTGS1NR4A2RXRB | |
| SCHEMBL8559262 | 0.86 | NR4A2 (0.40) | RXRAPTGS2PTGS1NR4A2RXRB | |
| SCHEMBL8560188 | 0.85 | PTGS2 (0.47) | RXRAPTGS2PTGS1NR4A2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699192-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-06 | — | — | EP | claimed |
| WO-1994027980-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1994-12-08 | — | — | WO | claimed |
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |