Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | DRD1 | P21728 | 7/20 | 0.37 |
| ▸ | DRD5 | P21918 | 7/20 | 0.37 |
| ▸ | DRD4 | P21917 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | DRD3 | P35462 | 6/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8563489 | 0.99 | TMEM97 (0.38) | TMEM97SIGMAR1DRD1DRD5DRD4 | |
| SCHEMBL8560519 | 0.90 | TMEM97 (0.43) | TMEM97SIGMAR1NOTUMHRH3SLC6A2 | |
| Hydrochloric Acid SCHEMBL8561496 | 0.90 | TMEM97 (0.43) | TMEM97SIGMAR1NOTUMHRH3SLC6A2 | |
| SCHEMBL8565814 | 0.90 | NOTUM (0.39) | TMEM97SIGMAR1DRD1DRD5DRD4 | |
| SCHEMBL8563033 | 0.89 | HTR6 (0.45) | DRD1DRD2CTSGCMA1 | |
| Hydrochloric Acid SCHEMBL8562266 | 0.89 | NOTUM (0.39) | TMEM97SIGMAR1DRD1DRD5DRD4 | |
| Hydrochloric Acid SCHEMBL8559384 | 0.89 | HTR6 (0.44) | CTSGCMA1 | |
| SCHEMBL8563454 | 0.86 | HTR6 (0.41) | CTSGCMA1 | |
| SCHEMBL8575396 | 0.84 | CTSG (0.36) | CTSGCMA1 | |
| Acetic Acid SCHEMBL8562511 | 0.84 | HTR6 (0.40) | CTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |