Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8561496 | 0.99 | TMEM97 (0.43) | TMEM97SIGMAR1SLC6A2HRH2HRH1 | |
| SCHEMBL8559521 | 0.90 | TMEM97 (0.39) | TMEM97SIGMAR1SLC6A2HRH3NOTUM | |
| Hydrochloric Acid SCHEMBL8563489 | 0.90 | TMEM97 (0.38) | TMEM97SIGMAR1SLC6A2HRH3NOTUM | |
| SCHEMBL8565814 | 0.88 | NOTUM (0.39) | TMEM97SIGMAR1SLC6A2HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL8562266 | 0.87 | NOTUM (0.39) | TMEM97SIGMAR1SLC6A2HRH2HRH1 | |
| SCHEMBL8563652 | 0.81 | ALDH1A1 (0.37) | TMEM97SIGMAR1SLC6A2HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL8564425 | 0.81 | ALDH1A1 (0.37) | TMEM97SIGMAR1SLC6A2HRH2HRH1 | |
| SCHEMBL8563033 | 0.80 | HTR6 (0.45) | ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL8559384 | 0.79 | HTR6 (0.44) | ALDH1A1GAA | |
| SCHEMBL8558617 | 0.78 | HTR6 (0.42) | SLC6A2HTR2CNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |