Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577383 | 0.85 | MAPT (0.36) | CTSGCMA1GAAALDH1A1L3MBTL1 | |
| SCHEMBL8559521 | 0.84 | TMEM97 (0.39) | CTSGCMA1 | |
| Hydrochloric Acid SCHEMBL8563489 | 0.83 | TMEM97 (0.38) | CTSGCMA1 | |
| SCHEMBL8563033 | 0.83 | HTR6 (0.45) | CTSGCMA1GAAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8559384 | 0.83 | HTR6 (0.44) | CTSGCMA1GAAALDH1A1L3MBTL1 | |
| SCHEMBL8563454 | 0.82 | HTR6 (0.41) | CTSGCMA1TSHR | |
| SCHEMBL8520116 | 0.82 | L3MBTL1 (0.33) | CTSGCMA1GAAALDH1A1L3MBTL1 | |
| Acetic Acid SCHEMBL8562511 | 0.81 | HTR6 (0.40) | CTSGCMA1 | |
| SCHEMBL8571584 | 0.79 | CTSG (0.39) | CTSGCMA1GAAALDH1A1L3MBTL1 | |
| SCHEMBL8575092 | 0.79 | CTSG (0.43) | CTSGCMA1GAAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |