Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4210863 | 0.75 | KIF11 (0.44) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL403808 | 0.72 | MEN1 (0.54) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL1202543 | 0.72 | IMPDH2 (0.63) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL25034150 | 0.72 | TUBB4A (0.68) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20017671 | 0.72 | CLK1 (0.58) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL2118588 | 0.71 | ENPP3 (0.43) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8561260 | 0.71 | MEN1 (0.55) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6797540 | 0.71 | LRRK2 (0.53) | ALDH1A1KDM4ERAB9ANPC1MAPK1 | |
| SCHEMBL6428705 | 0.71 | MAPT (0.51) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL2929592 | 0.71 | IMPDH2 (0.46) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821675-A1 | NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033176-A1 | NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-10-24 | — | — | WO | disclosed |