Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FHIT | P49789 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8564478 | 0.99 | FHIT (0.36) | FHITEGFRTMEM97SIGMAR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL8564923 | 0.91 | INSR (0.34) | FHITEGFRTMEM97SIGMAR1MEN1 | |
| SCHEMBL8563652 | 0.91 | ALDH1A1 (0.37) | TMEM97SIGMAR1KMT2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8564425 | 0.90 | ALDH1A1 (0.37) | TMEM97SIGMAR1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8569209 | 0.89 | HTR6 (0.37) | FHITEGFRKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8563251 | 0.89 | ESR1 (0.39) | FHITEGFRTMEM97SIGMAR1MEN1 | |
| Iodide SCHEMBL8600502 | 0.87 | CCR5 (0.41) | TMEM97SIGMAR1SMN1; SMN2HDAC6HRH3 | |
| Hydrochloric Acid SCHEMBL8566138 | 0.87 | CCR5 (0.41) | TMEM97SIGMAR1ALDH1A1HDAC6HRH3 | |
| Hydrochloric Acid SCHEMBL8565530 | 0.85 | NOTUM (0.33) | TMEM97SIGMAR1NOTUMMCHR1CYP2D6 | |
| Acetic Acid SCHEMBL8568344 | 0.84 | HTR6 (0.34) | FHITHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |