Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | P4HB | P07237 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494831 | 0.87 | MEN1 (0.47) | MEN1KMT2AEGFRPIM1CA1 | |
| SCHEMBL10490935 | 0.85 | HDAC4 (0.46) | MEN1KMT2AEGFRPIM1CA1 | |
| SCHEMBL8569425 | 0.79 | MEN1 (0.48) | MEN1KMT2AEGFRPIM1P4HB | |
| SCHEMBL10490941 | 0.77 | NPC1 (0.47) | P4HBTP53MAPTHPGD | |
| SCHEMBL9421974 | 0.75 | ALDH1A1 (0.47) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL10490943 | 0.75 | HDAC4 (0.47) | P4HBCA1CA2TSHRKDM4E | |
| SCHEMBL8382011 | 0.72 | MEN1 (0.84) | MEN1KMT2AEGFRPIM1P4HB | |
| SCHEMBL8559808 | 0.72 | ALDH1A1 (0.52) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL14113261 | 0.72 | MAOA (0.56) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL10490946 | 0.71 | KMT2A (0.53) | MEN1KMT2AEGFRPIM1P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843097-A | ANTITUMOR AGENTS, SKIN DISORDERS, ANTIINFLAMMATORY AGENTS | GROUPEMENT D'INTERET ECONOMIQUE DIT: CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-06-27 | — | — | US | claimed |
| US-4889865-A | COSMETICS, SKIN DISORDERS, ANTICARCINOGENIC AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-12-26 | — | — | US | disclosed |
| US-4843097-A | ANTITUMOR AGENTS, SKIN DISORDERS, ANTIINFLAMMATORY AGENTS | GROUPEMENT D'INTERET ECONOMIQUE DIT: CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-06-27 | — | — | US | disclosed |