Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015385 | 0.86 | L3MBTL1 (0.34) | MAPTSMN1; SMN2 | |
| SCHEMBL8556221 | 0.85 | TRPV4 (0.32) | TRPV4SMN1; SMN2 | |
| SCHEMBL6998020 | 0.85 | GNRHR (0.32) | RIPK2MAPT | |
| SCHEMBL8107121 | 0.81 | CCR4 (0.35) | — | |
| SCHEMBL9642094 | 0.79 | JAK1 (0.35) | TRPV4 | |
| SCHEMBL8118040 | 0.77 | PDE4D (0.32) | PDE4DPDE4B | |
| SCHEMBL8883188 | 0.77 | NPSR1 (0.34) | SMN1; SMN2 | |
| SCHEMBL9641272 | 0.75 | — | — | |
| SCHEMBL9642203 | 0.75 | — | — | |
| SCHEMBL8113240 | 0.74 | LMNA (0.36) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2598540-B2 | — | — | 1997-04-09 | — | — | JP | claimed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | claimed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | claimed |
| EP-0537611-B1 | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOW AGROSCIENCES LLC (US) | 1998-08-12 | — | — | EP | disclosed |
| US-5488109-A | 5-alkoxy[1,2,4]triazolo[1,5-c]pyrimidine-2(3H)--thione compounds and their use in the preparation of and 2-chlorosulfonyl-5-alkoxy[1,2,4]triazolo[1,5-c]-pyrimidine compounds | DOWELANCO (US) | 1996-01-30 | — | — | US | disclosed |
| EP-0678092-A1 | 5-ALKOXY 1,2,4]TRIAZOLO 1,5-C]PYRIMIDINE-2(3H)-THIONE COMPOUNDS AND THEIR USE IN THE PREPARATION OF 2,2'-DITHIOBIS(5-ALKOXY 1,2,4]TRIAZOLO 1,5-C]-PYRIMIDINE) AND 2-CHLOROSULFONYL-5-ALKOXY 1,2,4]TRIAZOLO 1,5-C]PYRIMIDINE COMPOUNDS | DOWELANCO (US) | 1995-10-25 | — | — | EP | disclosed |
| WO-1995012596-A1 | 5-ALKOXY[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE-2(3H)-THIONE COMPOUNDS AND THEIR USE IN THE PREPARATION OF 2,2'-DITHIOBIS(5-ALKOXY[1,2,4]TRIAZOLO[1,5-C]-PYRIMIDINE) AND 2-CHLOROSULFONYL-5-ALKOXY[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE COMPOUNDS | DOWELANCO (US) | 1995-05-11 | — | — | WO | disclosed |
| EP-0343752-B1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DOWELANCO (US) | 1993-12-01 | — | — | EP | disclosed |
| EP-0537611-A1 | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOWELANCO (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5177206-A | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOWELANCO (US) | 1993-01-05 | — | — | US | disclosed |
| US-5163995-A | For use with grassy crops and soybeans | DOWELANCO (US) | 1992-11-17 | — | — | US | disclosed |
| US-5010195-A | From 5-alkoxy-1,2,4-triazolo(1,5-c)pyrimidine | THE DOW CHEMICAL COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | disclosed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | disclosed |