SCHEMBL6998020

SCHEMBL6998020

CCOc1nc(F)cc2nc(S(=O)(=O)Cl)nn12

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 1/20 0.32
RIPK2 O43353 2/20 0.31
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
AHR P35869 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8107436 0.88 ALDH1A1 (0.32) RIPK2ALDH1A1KDM4EPOLBMAPT
SCHEMBL8559900 0.85 PDE4D (0.33) RIPK2MAPT
SCHEMBL8015385 0.85 L3MBTL1 (0.34) ALDH1A1KDM4EPOLBMAPTHPGD
SCHEMBL8030891 0.85 TRPV4 (0.30)
Diclosulam SCHEMBL116344 0.81 GNRHR (0.35) GNRHRALDH1A1NPSR1
SCHEMBL6999983 0.80 TSHR (0.36) GNRHRALDH1A1KDM4EPOLB
SCHEMBL8848572 0.78 GNRHR (0.34) GNRHRALDH1A1KDM4E
SCHEMBL9642094 0.78 JAK1 (0.35)
SCHEMBL8848901 0.78 LMNA (0.34) GNRHRALDH1A1KDM4EPOLBMAPT
SCHEMBL29690333 0.77 NUDT1 (0.35) RIPK2ALDH1A1KDM4EPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0888297-B1 N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS DOW AGROSCIENCES LLC (US) 2000-08-30 EP claimed
US-5973148-A N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds DOW AGROSCIENCES LLC (US) 1999-10-26 US claimed
EP-0343752-B1 Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates DOWELANCO (US) 1993-12-01 EP claimed
US-5163995-A For use with grassy crops and soybeans DOWELANCO (US) 1992-11-17 US claimed
CN-108349986-B Novel crystal form of diclosulam, preparation method and application thereof 江苏龙灯化学有限公司 2022-03-01 CN disclosed
US-9643973-B1 Crystalline form of diclosulam, a process for its preparation and use of the same ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-05-09 US disclosed
EP-1066289-B1 PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS DOW AGROSCIENCES LLC (US) 2003-11-19 EP disclosed
CN-1091100-C N-arylsulfilimine compounds and their use as catalysts for the preparation of N-arylarylsulfonamide compounds DOW AGROSCIENCES LLC (US) 2002-09-18 CN disclosed
EP-1066289-A1 PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS Dow AgroSciences LLC (US) 2001-01-10 EP disclosed
US-6162915-A Process for heterocyclic sulfonyl chloride compounds DOW AGROSCIENCES LLC (US) 2000-12-19 US disclosed
US-6114580-A N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds DOW AGROSCIENCES LLC (US) 2000-09-05 US disclosed
US-6114580-A N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds DOW AGROSCIENCES LLC (US) 2000-09-05 US disclosed
EP-0678092-A1 5-ALKOXY 1,2,4]TRIAZOLO 1,5-C]PYRIMIDINE-2(3H)-THIONE COMPOUNDS AND THEIR USE IN THE PREPARATION OF 2,2'-DITHIOBIS(5-ALKOXY 1,2,4]TRIAZOLO 1,5-C]-PYRIMIDINE) AND 2-CHLOROSULFONYL-5-ALKOXY 1,2,4]TRIAZOLO 1,5-C]PYRIMIDINE COMPOUNDS DOWELANCO (US) 1995-10-25 EP disclosed
US-5461153-A 2-alkoxy-4-hydrazinopyrimidine compounds DOWELANCO (US) 1995-10-24 US disclosed
US-5447905-A Postemergence herbicides DOWELANCO (US) 1995-09-05 US disclosed
US-5447905-A Postemergence herbicides DOWELANCO (US) 1995-09-05 US disclosed
WO-1995012596-A1 5-ALKOXY[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE-2(3H)-THIONE COMPOUNDS AND THEIR USE IN THE PREPARATION OF 2,2'-DITHIOBIS(5-ALKOXY[1,2,4]TRIAZOLO[1,5-C]-PYRIMIDINE) AND 2-CHLOROSULFONYL-5-ALKOXY[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE COMPOUNDS DOWELANCO (US) 1995-05-11 WO disclosed
WO-1995012596-A1 5-ALKOXY[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE-2(3H)-THIONE COMPOUNDS AND THEIR USE IN THE PREPARATION OF 2,2'-DITHIOBIS(5-ALKOXY[1,2,4]TRIAZOLO[1,5-C]-PYRIMIDINE) AND 2-CHLOROSULFONYL-5-ALKOXY[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE COMPOUNDS DOWELANCO (US) 1995-05-11 WO disclosed
EP-0343752-B1 Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates DOWELANCO (US) 1993-12-01 EP disclosed
US-5163995-A For use with grassy crops and soybeans DOWELANCO (US) 1992-11-17 US disclosed