Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891654 | 0.86 | MAPT (0.36) | POLBMEN1MAPTMAPK1CASP3 | |
| SCHEMBL7812720 | 0.73 | KMT2A (0.32) | MEN1KMT2A | |
| SCHEMBL260978 | 0.71 | KDM4E (0.50) | MEN1MAPTMAPK1KMT2A | |
| SCHEMBL8891018 | 0.71 | — | — | |
| SCHEMBL10880408 | 0.70 | TTR (0.49) | POLBMEN1MAPTMAPK1CASP3 | |
| SCHEMBL6564497 | 0.67 | KMT2A (0.48) | POLBMEN1MAPTKMT2ANPC1 | |
| SCHEMBL3320871 | 0.67 | ALOX15 (0.40) | MEN1MAPTKMT2A | |
| SCHEMBL6924446 | 0.66 | RAB9A (0.46) | POLBMEN1MAPTKMT2ARAB9A | |
| SCHEMBL9198371 | 0.65 | MAOA (0.34) | — | |
| SCHEMBL2489203 | 0.63 | KMT2A (0.60) | POLBMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847394-A1 | 2-CYCLOHEXANE-1,3-DIONE BENZOYL DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-17 | — | — | EP | disclosed |
| WO-1997009324-A1 | 2-CYCLOHEXANE-1,3-DIONE BENZOYL DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-13 | — | — | WO | disclosed |