Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563618 | 0.82 | ALDH1A1 (0.59) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL8564716 | 0.79 | MAPT (0.47) | MAPTALDH1A1AGTR1KMT2AMEN1 | |
| SCHEMBL8563079 | 0.79 | NCOA1 (0.54) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL8566513 | 0.75 | CASP6 (0.44) | MAPTALDH1A1ABCG2KMT2AMEN1 | |
| SCHEMBL8564524 | 0.75 | MAPT (0.43) | MAPTALDH1A1AGTR1KMT2AMEN1 | |
| SCHEMBL8569274 | 0.74 | MEN1 (0.43) | MAPTALDH1A1ABCG2KMT2AMEN1 | |
| SCHEMBL27444565 | 0.74 | MAPT (0.51) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL3298254 | 0.73 | KMT2A (0.54) | MAPTALDH1A1ABCG2KMT2AMEN1 | |
| SCHEMBL8568306 | 0.73 | TACR3 (0.63) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| Quinoline SCHEMBL27446167 | 0.73 | ALDH1A1 (0.50) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |