Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | RXRG | P48443 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | DVL1 | O14640 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053391 | 0.88 | DVL1 (0.44) | RXRARXRBRXRGFFAR4MAP4K4 | |
| SCHEMBL8560143 | 0.76 | RXRA (0.40) | RXRARXRBRXRGFFAR4FFAR1 | |
| SCHEMBL9056734 | 0.76 | RXRA (0.44) | RXRARXRBRXRGFFAR4FFAR1 | |
| Hydrochloric Acid SCHEMBL20509927 | 0.74 | RXRA (0.50) | RXRARXRBRXRGFFAR1MLNR | |
| SCHEMBL9255613 | 0.74 | ITGB3 (0.58) | RXRARXRBRXRGMAP4K4TBXAS1 | |
| Hydrochloric Acid SCHEMBL8564229 | 0.73 | MAPK9 (0.38) | RXRARXRBRXRGFFAR4DVL1 | |
| SCHEMBL8563938 | 0.73 | RXRA (0.43) | RXRARXRBRXRGFFAR1MLNR | |
| SCHEMBL8562408 | 0.73 | S1PR1 (0.44) | RXRARXRBRXRGFFAR1MLNR | |
| Hydrochloric Acid SCHEMBL8560694 | 0.72 | RXRA (0.39) | RXRARXRBRXRGTBXAS1FFAR1 | |
| Hydrochloric Acid SCHEMBL8567619 | 0.71 | FFAR4 (0.36) | RXRARXRBRXRGFFAR4DVL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | disclosed |