SCHEMBL856024

SCHEMBL856024

CC(C)C[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)O.CSCC[C@H](NC=O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FNTA P49354 9/20 0.54
FNTB P49356 9/20 0.54
PGGT1B P53609 7/20 0.54
LTA4H P09960 1/20 0.50
FPR1 P21462 1/20 0.49
FPR2 P25090 1/20 0.49
MME P08473 1/20 0.48
ANPEP P15144 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18106731 1.00 FNTA (0.54) FNTAFNTBPGGT1BLTA4HFPR1
SCHEMBL30051234 0.91 FNTA (0.58) FNTAFNTBPGGT1BLTA4H
N-Formylmethionyl-Leucylphenylalanine SCHEMBL17202476 0.89 FPR1 (0.61) LTA4HFPR1FPR2MME
Phenylalanine SCHEMBL304849 0.89 LTA4H (0.50) FNTAFNTBPGGT1BLTA4HFPR1
N-Formylmethionyl-Leucylphenylalanine SCHEMBL39528 0.89 FPR1 (0.61) LTA4HFPR1FPR2MME
Dl-Phenylalanine SCHEMBL7222094 0.89 LTA4H (0.50) FNTAFNTBPGGT1BLTA4HFPR1
N-Formylmethionyl-Leucylphenylalanine SCHEMBL4592799 0.89 FPR1 (0.61) LTA4HFPR1FPR2MME
N-Formylmethionyl-Leucylphenylalanine SCHEMBL39529 0.89 FPR1 (0.61) LTA4HFPR1FPR2MME
N-Formylmethionyl-Leucylphenylalanine SCHEMBL9903983 0.89 FPR1 (0.61) LTA4HFPR1FPR2MME
N-Formylmethionyl-Leucylphenylalanine SCHEMBL4969844 0.89 FPR1 (0.61) LTA4HFPR1FPR2MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250157661-A1 MONITORING INFLAMMATION STATUS MOLOGIC LIMITED (GB) 2025-05-15 US disclosed
EP-4396229-A1 ANTI-CECAM6 ANTIBODIES WITH REDUCED SIDE-EFFECTS Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2024-07-10 EP disclosed
EP-4381064-A1 COMPOUND AND METHOD FOR A SPECIFIC TARGETING OF THE HAXI GENE Eberhard Karls Universität Tübingen, Medizinische Fakultät (DE) 2024-06-12 EP disclosed
EP-4376837-A1 COMPOUNDS FOR NEUTROPHIL ROS INHIBITION Immunyx Pharma Ltd. (IL) 2024-06-05 EP disclosed
EP-4347128-A2 METHOD AND SYSTEM FOR SINGLE-CELL BIOPHYSICAL PROFILING USING A MICROFLUIDIC DEVICE Nanyang Technological University (SG) 2024-04-10 EP disclosed
US-20240101618-A1 IMMUNOMODULATORY PEPTIDE INSTITUT NATIONAL UNIVERSITAIRE JEAN-FRANCOIS CHAMPOLLION (FR) 2024-03-28 US disclosed
WO-2024028436-A1 NOVEL INTERLEUKIN-17A (IL-17A)-DERIVED PEPTIDE AND NEUTRALIZING ANTIBODY (AB17-IPL-1) THE UNIVERSITY OF BIRMINGHAM (GB) 2024-02-08 WO disclosed
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-01-25 US disclosed
EP-4259776-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE Purdue Research Foundation (US) 2023-10-18 EP disclosed
US-11753452-B2 Immunomodulatory peptide INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE 2023-09-12 US disclosed
US-7842795-B2 Gene sequence coding formyl peptide receptor binding protein; diagnosing cancer, wound bone healing, obesity, acute heart failure, hypotension, hypertension, urinary retention, osteoporosis, restenosis, atherosclerosis, thrombosis, cardiovascular, autoimmune and nervous system disorders EUROSCREEN S.A. (BE) 2010-11-30 US disclosed
WO-2010134014-A1 BRIDGED SPIRO [2.4] HEPTANE DERIVATIVES AS ALX RECEPTOR AND/OR FPRL2 AGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2010-11-25 WO disclosed
EP-1607745-B1 Ligand for G-protein coupled receptor FPRL2 and uses thereof EUROSCREEN SA (BE) 2010-02-24 EP disclosed
US-7659251-B2 Ligand for G-protein coupled receptor FPRL2 OGEDA SA (BE) 2010-02-09 US disclosed
US-20100009406-A1 Nucleic acids encoding a heme binding protein polypeptide OGEDA SA (BE) 2010-01-14 US disclosed
US-7582416-B2 Detecting of formyl peptide receptor like-2 (FPRL2) polypeptide activity using a heme binding protein (HBP) polypeptide as a modulating agents of polypeptide activity;. antibodies against FPRL2; drug screening for treating diseases characterized by dysregulation of FPRL2 polypeptide signal transduction OGEDA SA (BE) 2009-09-01 US disclosed
US-20090053739-A1 Ligand for G-protein coupled receptor FPRL2 and uses thereof OGEDA SA (BE) 2009-02-26 US disclosed
EP-2020604-A1 Ligand for G-protein coupled receptor FPRL2 and uses thereof Euroscreen S.A. (BE) 2009-02-04 EP disclosed
US-20060078559-A1 Ligand for G-protein coupled receptor FPRL2 and uses thereof OGEDA SA (BE) 2006-04-13 US disclosed
EP-1607745-A2 Ligand for G-protein coupled receptor FPRL2 and uses thereof Euroscreen S.A. (BE) 2005-12-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 FNTA 3635/4885FNTB 3019/4885PGGT1B 3961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.